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Values are the mean of two or more assays standard deviation. Selectivity index (SI) CC50/EC50. c Values in parentheses are the number of atoms beyond the phosphonate oxygen; the number after the colon is the number of double bonds in the alkyl chain. Source: Adapted from Keith et al.51

Inherent patterns of the sink movement are exploited in reference 52 for the design of robust and energy-ef cient routing This work assumes that there is a certain degree of predictability in the sink movement, such as the routine route of a ranger patrolling a forest Sensor nodes learn about the sink whereabouts at given times via statistics techniques as well as methods from distributed reinforcement learning In reference 50 a model for sink movements is presented where the sinks, called observers, move along the same route repeatedly and collect data from the sensors The sensed data are collected while the observer traverses the network In particular, when passing by sensor nodes, the observer wakes them up and receives their data (if any) The authors describe a prototype system developed at Rice University where the observers are carried by shuttles, and the sensors are spread out throughout the campus.

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Task (ii) has the shortest deadline (16 bit periods or 59 s), so I will implement this as an ISR. In fact with a hard deadline as short as this, it would be best to use the ARM processor s FIQ interrupt. The other tasks must run in a thread context. It would be inef cient to schedule a thread at this frequency it would use around 10% of the processor time context switching. It is also unnecessary. Instead, task (iii) will be triggered every 10 receive interrupts. The deadline for task (iii) depends on how much buffering is used. If there is enough buffering for 480 sample pairs (around 2 K) the deadline would be 320*3.69 s = 1180 s, since the task is triggered when there are 160 sample pairs available and must complete before the buffer lls. Tasks (i) and (iv) are triggered by the per-frame interrupt and need to complete quickly enough to set up hardware for the following frame. A convenient time for the per-frame interrupt is two timeslots into the frame, since it then does not clash with either the receive or transmit windows and allows six timeslots for any setup to complete before the next frame. This is 3.460 ms. However, 500 s is required for the synthesizer to lock before the next receive and so the deadline for tasks P and Q is 2.9 ms. So task P and Q should have lower priority than task F. In fact in this case the same thread could be used for all three tasks since these tasks never execute simultaneously anyway.

with activity declining sharply at 22 and 24 atoms The oxyethyl analogues of CDV (ODE- and OLE-CDV) were generally more active than their oxypropyl counterparts (ODP- and OLP-CDV) even though they differ in the overall numbers of atoms by only one methylene The enhancement in activity of the ether lipid esters appear to be due to their greater uptake into cells, resulting in a signi cant increase of intracellular levels of CDV52 As summarized above, a number of these analogues had signi cantly enhanced activity and selectivity indices, suggesting that the best of these analogues need to be evaluated for their oral ef cacy in animal models of orthopoxvirus disease, particularly since the relative oral bioavailability of HDP-CDV and ODE-CDV ranges from 88% to 97%.

In particular, the authors determine the transmission range needed to collect data from a prede ned percentage of the sensor nodes, given the observer speed, the time required to transmit a packet, and different traf c patterns The correlation among the various system parameters is investigated analytically Network-controlled sink mobility for reducing energy consumption and for maximizing the lifetime of a sensor network has been considered initially in reference 53 and then in references 54 56, 9 and 10 In these works the sink moves among the (static) sensor nodes and, while sojourning at given locations, collects data that are sent to it via multihop routes The rst work concerns minimizing energy consumption An ILP model is presented that determines the locations of multiple sinks as well.

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